Estrogen Replacement

By Jake Alexandre


It is a replacement therapy for postmenopausal women are a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex hormone, their name comes from estrus/oistros (period of fertility for female mammals) + gen/gonos = to generate. estriol is the primary estrogen of pregnancy. In the body these are all produced from androgens through actions of enzymes. Estrogens are used as part of some oral contraceptives, in estrogen replacement therapy for postmenopausal women, and in hormone replacement therapy for Tran's women.

Menopause is the result of changing hormones, specifically estrogen and progesterone. In women, these characteristics include breasts, a widened pelvis, and increased amounts of body fat in the buttock, thigh and hip region. Estrogen also contributes to the fact that women have less facial hair and smoother skin then men. It regulates the menstrual cycle and prepares the uterus for pregnancy by enriching and thickening the endometrial. Two hormones, the luteinizing hormone (LH) and the follicle stimulating hormone (FSH), help to control how the body produces estrogen in women who ovulate.

In females, synthesis of estrogens starts in theca interna cells in the ovary, by the synthesis of androstenedione from cholesterol. Androstenedione is a substance of moderate androgenic activity. This compound crosses the basal membrane into the surrounding granulosa cells, where it is converted to estrone or estradiol, either immediately or through testosterone. The conversion of testosterone to estradiol, and of androstenedione to estrone, is catalyzed by the enzyme aromatase.

Menopause is the result of changing hormones, specifically estrogen and progesterone. And menopause is directly linked to the functioning of estrogen. Basically the estrogen level remains relatively the same during 25 years, after which it will decrease constantly. Since the number of ovules that mature in the ovary decrease as women get older, the formation of estrogen also decreases after menopause, estradiol production drops to a very low but constant level. When the estrogen levels decrease and the menopause starts, then the main risks become osteoporosis and arteriosclerosis. This is the reason why doctors tend to prescribe estrogen replacement as a therapy Estrogen replacement is considered as drug that would improve the quality of life during menopause.

Estrogen dominance is often associated with symptoms such as food cravings, bloating, weight gain, fatigue, mood swings, depression, cyclical migraine headaches, decreased sexual desire, menstrual cramps, short cycles, heavy menstrual bleeding, hair loss, fibroids, and endometriosis. There are different kinds of estrogen replacements Bioidentical HRT is associated with far fewer side effects than conventional HRT and there is intriguing evidence that it may reduce the risk of certain cancers. If the progesterone to estrogen ratio is unbalanced, favoring excess estrogen, a woman may become susceptible to an increased risk of fibrocystic breast disease and other health problems.




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